Beyond Amphiphilicity RTG 2670: Self-Organization of Soft Matter via Multiple Noncovalent Interactions
Beyond Amphiphilicity

CMM for BEAM: Native mass spectrometry to study protein-ligand interactions

CMM for BEAM: Native mass spectrometry to study protein-ligand interactions

Supervisor: Prof. Carla Schmidt
Event Date: 29.3.2022 – 31.3.2022

Day 1:
• Lecture (approx. 90 mins): Introduction to mass spectrometry, protein identification, structural MS (basics of native MS)
• Wet lab: Sample preparation for native MS, preparing electrospray emitters for native MS, acquisition of native mass spectra (proteins and protein complexes)

Day 2:
• Lecture (approx. 90 mins): Advanced native MS experiments, data analysis, examples from literature
• Wet lab: Acquisition of native mass spectra (protein-ligand complexes), data analysis

Duration: 2 days (6-8 hours per day)
Participants: 2-4
Dates: 29. March and 31. March 2022

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